In vitro fertilization (IVF) with Preimplantation Genetic Testing (PGT)
In vitro fertilization (IVF) is one of the most successful assisted reproductive techniques for couples who are unable to conceive naturally. Preimplantation Genetic Testing (PGT) is an advanced technique used within the IVF process that allows for the genetic screening of embryos. This method offers significant advantages for couples who are carriers of genetic disorders, those who have experienced recurrent miscarriages, women of advanced maternal age, or couples with previous unsuccessful IVF attempts.
The treatment begins with the stimulation of the woman’s ovaries using medication and continues with the retrieval of the developed eggs. These collected eggs are then fertilized with sperm in a laboratory environment to create embryos. After a few days of development, a biopsy is performed on the embryos to collect samples for genetic analysis. Through PGT, chromosomal abnormalities, single-gene disorders, or structural genetic defects in the embryos can be identified.
Embryos identified as healthy are selected and transferred to the uterus in a way that maximizes the chances of pregnancy. This method not only increases the success rate of pregnancy but also reduces the risk of passing on genetic disorders, thereby enhancing the likelihood of having a healthy baby.
As a result, IVF treatment supported by PGT reduces genetic risks, paves the way for healthy pregnancies, and increases success rates—bringing families one step closer to fulfilling their dream of having a child.
Frequently Asked Questions
It is the process of genetically analyzing cells taken from embryos during in vitro fertilization (IVF) treatment.
No, the biopsy procedure performed with modern techniques does not harm the embryo.
By selecting healthy embryos, PGT increases the chances of pregnancy and reduces the risk of miscarriage.
Although PGT can be performed for anyone who wishes, it is especially recommended in the following cases:
In in vitro fertilization (IVF) treatment, Preimplantation Genetic Testing (PGT) is a technique that helps identify genetic abnormalities before embryo transfer. It is mainly used for embryo selection in certain patients to reduce the risk of genetic diseases. Indications for PGT may include:
1. A family history of serious genetic diseases or if the couple are carriers of a genetic disorder
2. Recurrent miscarriages
3. Women over the age of 35, where genetic testing of embryos may be recommended
4. Presence of chromosomal abnormalities in one or both partners
5. Repeated IVF failures
6. For gender selection purposes
While PGT is used to prevent genetic disorders and increase the chance of a healthy pregnancy, it may not be suitable for every patient. Therefore, a doctor will evaluate the individual’s condition to determine whether PGT is appropriate.
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